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What Serum to Use After Microneedling

What Serum to Use After Microneedling: Derm-Approved Guide for Glowing Results

 

After microneedling, skin thrives on deep hydration and barrier support. Low-molecular-weight hyaluronic acid serums are clinically shown to soothe, restore, and enhance healing.

Why Hyaluronic Acid?

  • Deep hydration: Holds up to 1,000× its weight in water.
  • Barrier repair: Supports extracellular matrix recovery.
  • Clinically proven: Study reported “enhanced hydration…within 20 minutes” sustained for weeks.
Hyaluronic acid dropper

Which Serums to Avoid

  • ❌ Retinoids & strong Vitamin C
  • ❌ AHAs/BHAs—glycolic, salicylic, lactic acids
  • ❌ Alcohol-based toners, heavy fragrance, essential oils

Avoid for 24–72 hrs to prevent irritation of fresh micro-channels.

Serums to avoid after microneedling

When & How Often to Apply

  • Immediately after: Within 5–10 minutes to soothe and hydrate.
  • Reapply: 2–3× daily for 3–5 days during healing.
  • Seal moisture: Finish with a gentle ceramide-rich moisturizer.

Extra Healing Ingredients

  • Ceramides & peptides: Support barrier recovery and firmness.
  • Botanicals: Hibiscus, aloe, lactobacillus ferment soothe inflammation.
Hyah Serum ingredients list

Our Pick: Beautimate Hyah Serum

  • 2% low-molecular sodium hyaluronate
  • Hibiscus extract + lactobacillus ferment
  • Lemon balm & orchid oil — vegan, fragrance-free
  • Made in USA

Shop Hyah Serum →

Beautimate Hyah Serum bottle

Supporting Clinical Evidence

“Fine lines… showed 25.8% decrease; hydration increased 15.4%; dermal density rose 14.2% and thickness 12.9%” — 12‑week HA microneedle patch study (Avcil et al., 2020) .

“Statistically significant improvements in wrinkle and skin hydration… no serious adverse effects” — 52‑subject cross‑linked HA patch trial (An et al., 2019) .

“Enhanced hydration, smoother texture, reduced erythema… within 20 minutes” — 16‑person HA35 + microneedling study (Kang et al., 2022 review) .

Safety: HA’s roles in wound healing and inflammation are well-established (Lee et al., 2019) .

FAQs

Vitamin C? Wait 3+ days for skin to settle and prevent irritation.

Makeup? Allow 24 hrs for micro‑channels to close fully.

SPF? Start mineral/physical sunscreen after 24 hrs to protect healing skin.

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